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專家名錄

專家名錄

TEACHING AREAS

  • Functional Foods & Nutraceuticals
  • Testing and Certification for Microbiological Testing
  • Food Toxicology
  • Human Physiology
  • Chinese Medicine
  • Pharmacology
  • Biostatistics

EMPLOYMENT

2017 - Present Head of Department, Department of Food and Health Sciences, Technological and Higher Education Institute of Hong Kong, Tsing Yi, Hong Kong
2016 - Present Associate Professor and Programme Leader for 1) BSc (Hons.) in Food Science and Safety and 2) BSc (Hons.) in Testing and Certification, Technological and Higher Education Institute of Hong Kong, Tsing Yi, Hong Kong
2014 - 2016 Assistant Professor and Programme Leader for BSc (Hons.) in Food Science and Safety, Technological and Higher Education Institute of Hong Kong, Tsing Yi, Hong Kong
2012 - 2014 Assistant Director, Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University.
2012 - 2014 Assistant Director, State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Shenzhen, China.
2005 - 2014 Instructor, Teaching Fellow, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University.
2008 - 2012 Scientific advisor of the pharmacology section, State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Shenzhen, China
2002 - 2006 Visiting Lecturer (part-time), Student Affairs Office, The Hong Kong Polytechnic University.

VISITING APPOINTMENTS

2017 - Present Adjunct Associate Professor, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University
2014 - Present Assistant Director, Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University
2014 - 2017 Visiting Assistant Professor, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University
2014 - 2017 Associate Director, State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Shenzhen, China

PROFESSIONAL SOCIETIES AND AFFILIATION

2014 - Present Technical Expert, The Hong Kong Q-Mark Council, Hong Kong
2012 - 2015 Internal vice-chairman, The Hong Kong Food Science and Technology Association, Hong Kong
2010 - 2012 Membership officer, The Hong Kong Food Science and Technology Association, Hong Kong

AWARDS

2007 - 2008 Outstanding Performance Staff Award, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University.
2001 - 2002 Outstanding Performance Staff Award, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University.

RESEARCH EXPERIENCE

Member of Editorial Board of the following journals

RESEARCH INTERESTS

  • Functional Foods & Neutraceuticals
  • Food Safety
  • Cardiovascular Physiology
  • Chinese Medicine
  • Pharmacology
  • Food Microbiology

SELECTED PUBLICATION

Research papers

Papers published in SCI Journals

  • Wu X, Chan SW, Ma J, Li P, Shaw PC, Lin G. (2018) Investigation of association of chemical profiles with the tracheobronchial relaxant activity of Chinese medicinal herb Beimu derived from various Fritillaria species. Journal of Ethnopharmacology. 210: 39-46.
  • Li S, Ai N, Shen M, Dang Y, Chong CM, Pan P, Kwan YW, Chan SW, Leung GPH, Hoi MPM, Hou T, Lee SM. (2017) Discovery of a ROCK inhibitor, FPND, which prevents cerebral hemorrhage through maintaining vascular integrity by interference with VE-cadherin. Cell Death Discovery. 3: 17051.
  • Chan JY, Zhou H, Kwan YW, Chan SW, Radis-Baptista G, Lee SM. (2017) Evaluation in zebrafish model of the toxicity of rhodamine B-conjugated crotamine, a peptide potentially useful for diagnostics and therapeutics. Journal of Biochemical and Molecular Toxicology. 31(11): e21964.
  • Gao L, Siu PM, Chan SW, Lai WKC. (2017) Cardiovascular protective effects of Salvianic Acid A in db/db mice with elevated homocysteine level. Oxidative Medicine and Cellular Longevity. 2017: 9506925.
  • Zhang H, Zhou XL, Wong MHY, Man KY, Pin WK, Yeung JHK, Kwan YW, Leung GPH, Hoi PM, Lee SMY, Chan CO, Mok DKW, Yu PHF, Chan SW*. (2017) Sichuan pepper attenuates H2O2-induced apoptosis via antioxidant activity and up-regulating heme oxygenase-1 gene expression in primary rat hepatocytes. Journal of Food Biochemistry. (Accepted).
  • Zhang H, Wu MY, Guo DJ, Wan CW, Chan SW*. (2017) Gui-ling-gao inhibits concanavalin A-induced inflammation by suppressing the expressions of iNOS and pro-inflammatory cytokines in mice isolated splenocytes. Journal of Food Biochemistry. 41: e12367.
  • Lam W, Wang Y, Chan PL, Chan SW, Tsang YF, Chua H, Yu PHF. (2017) Production of polyhydroxyalkanoates (PHA) using sludge from different wastewater treatment processes and the potential for medical and pharmaceutical applications. Environmental Technology. 38(13-14): 1779-1791.
  • Sham TT, Li MH, Chan CO, Zhang H, Chan SW, Mok DKW. (2017) Cholesterol-lowering effects of piceatannol, a stilbene from wine, using untargeted metabolomics. Journal of Functional Foods. 28: 127-137.
  • Zhou X, Cui G, Tseng HHL, Lee SMY, Leung GP, Chan SW, Kwan YW, Hoi MP. (2016) Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine.  Evidence-Based Complementary and Alternative Medicine. 2016: 9627258.
  • Zhou X, Choi PS, Yang JM, Or PMY, Hoi PM, Lee SMY, Leung GPH, Ngai SM, Kong SK, Ho HP, Wong MYM, Chan SW*, Yeung JHK, Kwan YW. (2016) Chemical and pharmacological evaluations on the extract of Scutellaria baicalensis Georgi (Huang-Qin) prepared by various extraction methods. SpringerPlus. 5: 1438.         
  • Liang WL, Pan YL, Cheng HL, Li TC, Yu PHF, Chan SW*. (2016) The microbiological quality of take-away raw salmon finger sushi sold in Hong Kong. Food Control. 69: 45-50.
  • Tang PC, Yang C, Li RW, Lee SM, Hoi MP, Chan SW, Kwan YW, Tse CM, Leung GP. (2016) Inhibition of human equilibrative nucleoside transporters by 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine. European Journal of Pharmacology. 791: 544-551.
  • Gao X, Li C, Tang YL, Zhang H, Chan SW*. (2016) Effect of Hedyotis diffusa water extract on protecting human hepatocyte cells (LO2) from H2O2-induced cytotoxicity. Pharmaceutical Biology. 54(7): 1148-1155.
  • Sun HY, Liu BB, Hu JY, Xu LJ, Chan SW, Chan CO, Mok DK, Zhang DM, Ye WC, Chen SB. (2016) Novel cycloartane triterpenoid from Cimicifuga foetida (Sheng ma) induces mitochondrial apoptosis via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation in human breast carcinoma MCF-7 cells. Chinese Medicine. 11: 1.
  • Li S, Dang Y, Zhou X, Huang B, Huang X, Zhang Z, Kwan YW, Chan SW, Leung GP, Lee SM, Hoi MP. (2015) Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway. Scientific Report. 5: 16815.
  • Poon CC, Li RW, Seto SW, Kong SK, Ho HP, Hoi MP, Lee SM, Ngai SM, Chan SW, Leung GP, Kwan YW. (2015) In vitro vitamin K2 and 1α,25-dihydroxyvitamin D3 combination enhances osteoblasts anabolism of diabetic mice. European Journal of Pharmacology. 767:30-40.
  • Yan CS, Wong IL, Chan KF, Kan JW, Chong TC, Law MC, Zhao Y, Chan SW, Chan TH, Chow LM. (2015) A New Class of Safe, Potent, and Specific P-gp Modulator: Flavonoid Dimer FD18 Reverses P-gp-Mediated Multidrug Resistance in Human Breast Xenograft in Vivo. Molecular Pharmaceutics. 12(10): 3507-3517.
  • Cui GZ, Shan LC, Chu IK, Li GH, Leung GPH, Wang YQ, Hoi PM, Kwan YW, Chan SW, Lee SMY. (2015) Identification of disulfide isomerase ERp57 as a target for small molecule cardioprotective agent. RSC Advances. 5: 74605-74610.
  • Guo YQ, Sun HY, Chan CO, Liu BB, Wu JH, Chan SW, Mok DK, Tse AK, Yu ZL, Chen SB. (2015) Centipeda minima (Ebushicao) extract inhibits PI3K-Akt-mTOR signaling in nasopharyngeal carcinoma CNE-1 cells. Chinese Medicine. 10: 26.
  • Yang RF, Zhao C, Chen X, Chan SW*, Wu JY. (2015) Chemical properties and bioactivities of Goji (Lycium barbarum) polysaccharides extracted by different methods. Journal of Functional Foods. 17: 903–909.
  • Li JJ, Zhou SY, Lam KH, Yu PHF, Lee SMY, Chan SW*. (2015) Cortex Fraxini (Qingpi) Protects Rat Pheochromocytoma (PC12) Cells Against 6-hydroxydopamine-induced Apoptosis. Parkinson's Disease. 2015: 532849.
  • Zhang SY, Chan SW, Zhou X, Chen XL, Mok DKW, Lin ZX, Wang YH. (2015) Meta-analysis of association between ALDH2 rs671 polymorphism and essential hypertension in Asian populations. Herz. 40(S2): 203-208.
  • Zhang LQ, Sa F, Chong CM, Wang Y, Zhou ZY, Chang CC, Chan SW, Hoi PM, Yuen Lee SM. (2015) Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3β pathways. Journal of Ethnopharmacology. 170: 5-15
  • Li RW, Yang C, Shan L, Zhang Z, Wang Y, Kwan YW, Lee SM, Hoi MP, Chan SW, Cheung AC, Cheung KH, Leung GP. (2015) Relaxation effect of a novel Danshensu/tetramethylpyrazine derivative on rat mesenteric arteries. European Journal of Pharmacology. 761: 153-160.
  • Li RW, Yang C, Chan SW, Hoi MP, Lee SM, Kwan YW, Leung GP. (2015) Relaxation effect of abacavir on rat basilar arteries. PLoS One. 10(4): e0123043.
  • Li S, Zhou XL, Dang YY, Kwan YW, Chan SW, Leung GPH, Lee SMY, Hoi MPM. (2015) Basal Flt1 tyrosine kinase activity is a positive regulator of endothelial survival and vascularization during zebrafish embryogenesis. Biochimica et Biophysica Acta - General Subjects. 1850(2): 373-384.
  • Wu J, Liu X, Chan CO, Mok DK, Chan SW*, Yu Z, Chen S. (2014) Petroleum ether extractive of the hips of Rosa multiflora ameliorates collagen-induced arthritis in rats. Journal of Ethnopharmacology. 157: 45-54.
  • Li S, Dang YY, Che GOL, Kwan YW, Chan SW, Leung GPH, Lee SMY, Hoi MPM. (2014) VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation. Toxicology and Applied Pharmacology. 280(3): 408-420.
  • Tang PC, Ng YF, Ho S, Gydad M, Chan SW*. (2014) Resveratrol and Cardiovascular Health - Promising Therapeutic or Hopeless Illusion? Pharmacological Research. 90: 88-115.
  • Li CM, Guo YQ, Dong XL, Li H, Wang B, Wu JH, Wong MS, Chan SW*. (2014) Ethanolic extract of Rhizome of Ligusticum Chuanxiong Hort. (Chuanxiong) enhances endothelium-dependent vascular reactivity in ovariectomized rats fed with high-fat diet. Food & Function. 5(10): 2475-2485.
  • Tang YL, Chan SW*. (2014) A Review of the Pharmacological Effects of Piceatannol on Cardiovascular Diseases. Phytotherapy Research. 28(11): 1581-1588.
  • Chan JYY, Tsui HT, Chung IYM, Chan RYK, Kwan YW, Chan SW*. (2014) Allicin protects rat cardiomyoblasts (H9c2 cells) from hydrogen peroxide-induced oxidative injury through inhibiting the generation of intracellular reactive oxygen species. International Journal of Food Sciences and Nutrition. 65(7): 868-873.
  • Li RWS, Yang C, Sit ASM, Kwan YW, Lee SMY, Hoi MPM, Chan SW, Hausman M, Vanhoutte PM, Leung GPH. (2014) Uptake and protective effects of ergothioneine in human endothelial cells. The Journal of Pharmacology and Experimental Therapeutics. 350(3): 691-700.
  • Ng YF, Tang PC, Sham TT, Lam WS, Mok DK, Chan SW*. (2014) Semen Astragali Complanati: An ethnopharmacological, phytochemical and pharmacological review. Journal of Ethnopharmacology. 155(1): 39-53.
  • Sham TT, Chan CO, Wang YH, Yang JM, Mok DKW, Chan SW*. (2014) A review on the traditional Chinese medicinal herbs and formulae with hyperlipidaemic effect. BioMed Research International. 2014:925302.
  • Li WY, Ng YF, Zhang H, Guo ZD, Guo DJ, Kwan YW, Leung GPH, Lee SMY, Yu PH, Chan SW*. (2014) Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis. Inflammopharmacology. 22(2):127-134.
  • Li RW, Yang C, Kwan YW, Chan SW, Lee SM, Leung GP. (2013) Involvement of organic cation transporter-3 and plasma membrane monoamine transporter in serotonin uptake in human brain vascular smooth muscle cells. Frontiers in Pharmacology. 4:14.
  • Zhang H, Li C, Kwok ST, Zhang QW, Chan SW*. (2013) A review of the pharmacological effects of the dried root of Polygonum cuspidatum (Huzhang) and its constituents. Evidence-Based Complementary and Alternative Medicine. 2013: 208349.
  • Chan GHH, Law BYK, Chu JMT, Yue KKM, Jiang ZH, Lau CW, Huang Y, Chan SW, Yue PYK, Wong RNS, (2013) Ginseng extracts restore high-glucose induced vascular dysfunctions by altering triglyceride metabolism and down-regulation of atherosclerosis-related genes. Evidence-Based Complementary and Alternative Medicine. 2013: 797310.
  • Seto SW, Au AL, Poon CC, Zhang Q, Li RW, Yeung JH, Kong SK, Ngai SM, Wan S, Ho HP, Lee SM, Hoi MP, Chan SW*, Leung GP, Kwan YW. (2013) Acute Simvastatin Inhibits K ATP Channels of Porcine Coronary Artery Myocytes. PLoS One. 8(6):  e66404.
  • Ng YF, Wong, SL, Cheng HL, Yu PHF, Chan SW*. (2013) The microbiological quality of ready-to-eat food in Siu Mei and Lo Mei shops in Hong Kong. Food Control. 34: 547-553.
  • Sham TT, Yuen ACY, Ng, YF, Chan CO, Mok DKW, Chan SW*. (2013) A Review of the Phytochemistry and Pharmacological Activities of Raphani Semen. Evidence-Based Complementary and Alternative Medicine. 2013: 636194.
  • Kwok CY, Li C, Cheng HL, Ng YF, Chan TY, Kwan YW, Leung GPH, Lee SMY, Mok DKW, Yu PHF, Chan SW*. (2013) Cholesterol Lowering and Vascular Protective Effects of Ethanolic Extract of Dried Fruit of Crataegus pinnatifida, hawthorn (Shan Zha), in Diet-induced Hypercholesterolaemic Rat Model. Journal of Functional Foods. 5: 1326-1335.
  • Li CM, Wu JH, Yang RF, Dong XL, He ZY, Tian XL, Guo DJ, Wong MS, Qiu TQ, Chan SW*. (2013) Ligusticum chuanxiong Prevents Ovariectomy-Induced Liver and Vascular Damages in Rats.  American Journal of Chinese Medicine. 41(4): 831-848.
  • Wu JH, Leung GPH, Kwan YW, Sham TT, Tang JY, Wang YH, Wan JB, Lee SMY, Chan SW*. (2013) Suppression of Diet-Induced Hypercholesterolaemia by Saponins from Panax notoginseng in Rats. Journal of Functional Foods. 5: 1159-1169.
  • Li WY, Chan RYK, Yu PHF, Chan SW*. (2013) Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes. Pharmaceutical Biology. 51(9): 1175-1181.
  • Li F, Wu JH, Wang QH, Shu YL, Wan CW, Chan CO, Mok DKW, Chan SW*. (2013) Gui-ling-gao, a traditional Chinese functional food, prevents oxidative stress-induced apoptosis in H9c2 cardiomyocytes. Food & Function. 4: 745-753.
  • Chan JYY, Yuen ACY, Chan RYK, Chan SW*. (2013) A Review of the Cardiovascular Benefits and Antioxidant Properties of Allicin. Phytotherapy Research. 27: 637-646.
  • Zhang H, Wu MY, Guo DJ, Wan CW, Lau CC, Chan CO, Mok DKW, Chan SW*. (2013) Gui-ling-gao (turtle jelly), a traditional Chinese functional food, exerts anti-inflammatory effects by inhibiting iNOS and pro-inflammatory cytokine expressions in splenocytes isolated from BALB/c mice. Journal of Functional Foods. 5: 625-632
  • Wan CW, Wong CNY, Pin WK, Wong MHY, Kwok CY, Chan RYK, Yu PHF, Chan SW*. (2013) Chlorogenic Acid Exhibits Cholesterol Lowering and Fatty Liver Attenuating Properties by Upregulating the Gene Expression of PPAR-a in Hypercholesterolemic Rats Induced with a High-Cholesterol Diet. Phytotherapy Research. 27: 545-551.
  • Li CM, Dong XL, Fan XD, Wu JH, Wang QH, Tian XL, Guo DJ, Wong MS, Qiu TQ, Chan SW* (2013) Aqueous Extract of Danshen (Salvia Miltiorrhiza Bunge) Protects Ovariectomized Rats Fed with High-fat Diet from Endothelial Dysfunction. Menopause. 20(1):100-109.
  • Guo DJ, Li F, Yu PHF, Chan SW*. (2013) Neuroprotective effects of luteolin against apoptosis induced by 6-hydroxy dopamine on rat pheochromocytoma PC12 cells. Pharmaceutical Biology.   51(2):190-196.
  • Chan SH, Chui CH, Chan SW, Kok SHL, Chan D, Tsoi MYT, Leung PHM, Lam AFY, Chan ASC, Lam KH, Tang JCO. (2013) Synthesis of 8-Hydroxyquinoline Derivatives as Novel Antitumor Agents. ACS Medicinal Chemistry Letter. 4: 170-174.
  • Wu JH, Wang QH, Li F, Shu YL, Chan CO, Mok DKW, Chan SW*. (2012) Suppression of Diet-Induced Hypercholesterolemia by Turtle Jelly, a Traditional Chinese Functional Food, in Rats. Evidence-Based Complementary and Alternative Medicine. 2012:320304
  • Zhou X, Chan SW, Tseng HL, Deng Y, Hoi PM, Choi PS, Or PM, Yang JM, Lam FF, Lee SM, Leung GP, Kong SK, Ho HP, Kwan YW, Yeung JH. (2012) Danshensu is the major marker for the antioxidant and vasorelaxation effects of Danshen (Salvia miltiorrhiza) water-extracts produced by different heat water-extractions. Phytomedicine. 19(14):1263-1269.
  • Chan E, Chan JYY, Wu JH, Wan CW, Leung GPH, Lee SMY, Kwan YW, Chan SW*. (2012) Serum nitric oxide synthase activity is a novel predictor of impaired vasorelaxation in rats. Clinical and Experimental Pharmacology and Physiology. 39(10): 894-896.
  • Chan SW*. (2012) Panax ginseng, Rhodiola rosea and Schisandra chinensis. International Journal of Food Sciences and Nutrition. 63 S1:75-81.
  • Kam TS, Wong CY, Kwan PL, Fat-Yiu W, Chiu SM, Chan SW, Yuen KS, Chan R. (2012) Effects and mechanism of turmeric vasorelaxation of the thoracic aorta in hypercholesterolemic rats. Journal of Medicinal Food. 15(2):190-199.
  • Zhang Y,  Hu G, Li S, Li ZH, Lam CO, Hong SJ, Kwan YW, Chan SW, Leung GP, Lee SM (2012) Pro-angiogenic activity of astragaloside IV in HUVECs in vitro and zebrafish in vivo. Molecular Medicine Reports. 5(3):805-811.
  • Tang WM, Chan E, Kwok CY, Lee YK, Wu JH, Wan CW, Chan RY, Yu PH, Chan SW*. (2012) A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit. Inflammopharmacology. 20(6):307-314.
  • Hu G, Siu SO, Li S, Chu IK, Kwan YW, Chan SW, Leung GP, Yan R, Lee SM (2012). Metabolism of calycosin, an isoflavone from Astragali Radix, in zebrafish larvae. Xenobiotica. 42(3):294-303.
  • Chan JY, Chan E, Chan SW*, Sze SY, Chan MF, Tsui SH, Leung KY, Chan RY, Chung IY. (2011) Enhancement of in vitro and in vivo anticancer activities of polysaccharide peptide from Grifola frondosa by chemical modifications. Pharmaceutical Biology. 49(11): 1114-1120.
  • Li S, Lou S, Lei BUW,  Chan TF, Kwan YW, Chan SW, Leung GPH, Tsui SKW, Lee SMY. (2011) Transcriptional Profiling of Angiogenesis Activities of Calycosin in Zebrafish. Molecular BioSystems. 7(11):3112-3121.
  • Yiu WF, Kwan PL, Wong CY, Kam TS, Chiu SM, Chan SW, Chan R. (2011) Attenuation of fatty liver and prevention of hypercholesterolemia by extract of Curcuma longa through regulating the expression of CYP7A1, LDL-receptor, HO-1, and HMG-CoA reductase. Journal of Food Sciences. 76(3):H80-H89.
  • Chan E, Liu XX, Guo DJ, Kwan YW, Leung GP, Lee SM, Chan SW*. (2011) Extract of Scutellaria baicalensis Georgi Root Exerts Protection Against Myocardial Ischemia-Reperfusion Injury in Rats. American Journal of Chinese Medicine. 39(4):693-704.
  • Chan YS, Cheng LN, Wu JH, Chan E, Kwan YW, Lee SM, Leung GP, Yu PH, Chan SW*. (2011) A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 19(5):245-254.
  • Wang N, Wan JB, Chan SW, Deng YH, Yu N, Zhang QW, Wang YT, Lee SM. (2011) Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion. Chinese Medicine. 13;6:37.
  • Wan CW, Lee YK, Kwok CY, Chan RYK, Yu PHF, Chan SW*. (2010) A validated HPLC method with dual wavelength detection on chlorogenic acid and internal standard in plasma and its application in pharmacokinetic study in rats. Journal of Liquid Chromatography & Related Technologies. 33:324-335.
  • Alex D, Leong EC, Zhang ZJ, Yan GTH, Cheng SH, Leong CW, Li ZH, Lam KH, Chan SW, Lee SMY. (2010) Resveratrol derivative, trans-3,5,4’-trimethoxystilbene, exerts antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2/KDR and cell-cycle modulation. Journal of Cellular Biochemistry. 109:339-346.
  • Wu JH, Li Q, Wu MY, Guo DJ, Chen HL, Chen SL, Seto SW, Au ALS, Poon CCW, Leung GPH, Lee SMY, Kwan YW, Chan SW* (2010) Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways. Journal of Nutritional Biochemistry. 21(7):613-620.
  • Seto SW, Lam TY, Or PMY, Lee WYW, Au ALS, Poon CCW, Chan SW, Yeung JHK, Leung GPH, Lee SMY, Ngai SM, Kwan YW. (2010) Folic acid consumption reduces resistin level and restores the blunted acetylcholine-induced aortic relaxation in obese/diabetic mice. Journal of Nutritional Biochemistry. 21(9):872-880.
  • Chan E, Wong CYK, Wan CW, Kwok CY, Wu JH, Ng KM, So CH, Au ALS, Poon CCW, Seto SW, Kwan YW, Yu PHF, Chan SW*. (2010) Evaluation of anti-oxidant capacity of root of Scutellaria baicalensis Georgi, in comparison with roots of Polygonum multiflorum Thunb and Panax ginseng CA Meyer. American Journal of Chinese Medicine. 38(4):815-827.
  • Kwok CY, Wong CNY, Yau, MYC, Yu PHF, Au ALS, Poon CCW, Seto SW, Lam TY, Kwan YW, Chan SW*. (2010) Consumption of dried fruit of Crataegus pinnatifida (hawthorn) suppresses high cholesterol diet-induced hypercholesterolemia in rats. Journal of Functional Foods. 2(3):179-186.
  • Yang C, Kwan YW, Au AL, Poon CC, Zhang Q, Chan SW, Lee SM, Leung GP. (2010) 14,15-Epoxyeicosatrienoic acid induces vasorelaxation through the prostaglandin EP(2) receptors in rat mesenteric artery. Prostaglandins and Other Lipid Mediators. 93(1-2):44-51.
  • Tang JY, Li S, Li ZH, Zhang ZJ, Hu G, Cheang LC, Alex D, Hoi MP, Kwan YW, Chan SW, Leung GP, Lee SM. (2010) Calycosin promotes angiogenesis involving estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway in zebrafish and HUVEC. PLoS One. 5(7):e11822.
  • Yang C, Kwan YW, Chan SW, Lee SM, Leung GP. (2010) Potentiation of EDHF-mediated relaxation by chloride channel blockers. Acta Pharmacologica Sinica. 31(10):1303-1311.
  • Poon CC, Seto SW, Au AL, Zhang Q, Li RW, Lee WY, Leung GP, Kong SK, Yeung JH, Ngai SM, Ho HP, Lee SM, Chan SW, Kwan YW. (2010) Mitochondrial monoamine oxidase-A-mediated hydrogen peroxide generation enhances 5-hydroxytryptamine-induced contraction of rat basilar artery. British Journal of Pharmacology. 161(5):1086-1098.
  • Meng Z, Chen SL, Seto SW, Kwan YW, Chan SW*. (2009) Correlation of Anti-oxidative property and Vaso-relaxation Effect of Major Active Constituents of Traditional Chinese Medicine. Pharmaceutical Biology. 47:366-371.
  • Seto SW, Lam TY, Tam HL, Au ALS, Chan SW, Wu JH, Yu PHF, Leung GPH, Ngai SM, Yeung JHK, Leung PS, Lee SMY, Kwan YW. (2009) Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db) mice. Phytomedicine. 16:426-436.
  • Seto SW, Lau WS, Lam HY, Au ALS, Chim SSC, Ngai SM, Chan SW, Leung DTN, Kwan YW. (2009) Role of monoamine oxidases in the exaggerated 5-hydroxytryptamine-induced tension development of human isolated preeclamptic umbilical artery. European Journal of Pharmacology. 605:129-137.
  • Yan LP, Zhuang YL, Chan SW, Chen SL, Shi GG. (2009) Analysis of the mechanisms underlying the endothelium-dependent antivasoconstriction of puerarin in rat aorta. Naunyn Schmiedebergs Arch Pharmacology. 379:587-597.
  • Li RWS, Seto SW, Au ALS, Kwan YW, Chan SW, Lee SMY, Tse CM, Leung GPH. (2009) Inhibitory effect of nonsteroidal anti-inflammatory drugs on adenosine transport in vascular smooth muscle cells. European Journal of Pharmacology. 612:15-20.
  • Li WY, Chan SW*, Guo DJ, Chung MK, Leung TY, Yu PHF. (2009) Water extract of Rheum officinale Baill. induces apoptosis in human lung adenocarcinoma A549 and human breast cancer MCF-7 cell lines. Journal of Ethnopharmacology. 124:251-256.
  • Li Q, Wu JH, Guo DJ, Cheng HL, Chen SL, Chan SW*. (2009) Suppression of diet-induced hypercholesterolemic atherosclerosis by scutellarin in rats. Planta Medica. 75:1203-1208.
  • Lam TY, Seto SW, Au ALS, Poon CCW, Lam HY, Lau MW, Chan SW, Ngai SM, Leung GPH, Lee, SMY, Tsui SKY, Kwan YW. (2009) Folic Acid Supplementation Modifies b-Adrenoceptor-Mediated in vitro Lipolysis of Obese/Diabetic (+db/+db) Mice. Experimental Biology and Medicine. 16:426-436.
  • Chan SW, Li S, Kwok CY, Benzie IFF, Szeto YT, Guo DJ. He XP, Yu PHF. (2008) Studies on the Antioxidant Activity of Chinese Medicinal Herbs. Pharmaceutical Biology. 48:587-595.
  • Guo DJ, Cheng HL, Chan SW, Yu PHF. (2008) Antioxidant activity and the total phenolic content of tonic Chinese Medicinal Herbs. Inflammopharmacology. 16: 1-7.
  • Chen C, Cheng YC, Yu CH, Chan SW, Cheung MK, Yu PHF. (2008) In vitro cytotoxicity, hemolysis assay, and biodegradation behavior of biodegradable poly(3-hydroxybutyrate)-poly(ethylene glycol)-poly(3-hydroxybutyrate) nanoparticles as potential drug carriers. Journal of Biomedical Materials Research. Part A. 87:290-298.
  • Seto SW, Lam TY, Leung GPH, Au ALS, Ngai SM, Chan SW, Kwan YW. (2007) Comparison of vascular relaxation, lipolysis and glucose uptake by peroxisome proliferator-activator receptor-g activation in +db/+m and +db/+db mice. European Journal of Pharmacology. 572:40-48.
  • Hao XN, Chan SW*, Chen SL. (2007) Detection of puerarin and danshensu in traditional Chinese medicinal preparation containing Pueraria lobata and Salvia miltiorrhiza by high-performance liquid chromatography. Journal of Liquid Chromatography and Related Technologies. 30:2779-2787.
  • Chan SW, Rudd JA, Lin G, Li P. (2007) Action of anti-tussive drugs on the emetic reflex of Suncus murinus (House Musk Shrew). European Journal of Pharmacology. 559:196-201.
  • Li WY, Chan SW*, Yu PHF, Guo DJ. (2007) Correlation between antioxidative power and anticancer activity in herbs from traditional Chinese medicine formulae with anticancer therapeutic effect. Pharmaceutical Biology. 45:541-546.
  • Seto SW, Au ALS, Lam TY, Chim SSC, Lee SMY, Wan S, Tjiu DCS, Shigemura N, Yim APC, Chan SW, Tsui SKW, Leung GPH, Kwan YW. (2007) Modulation by simvastatin of iberiotoxin-sensitive, Ca2+-activated K+ channels of porcine coronary artery smooth muscle cells. British Journal of Pharmacology. 151:987-997.
  • Yan LP, Chan SW*, Chan ASC, Chen SL, Ma XJ, Xu HX. (2006) Puerarin decreases serum total cholesterol and enhances thoracic aorta endothelial nitric oxide synthase expression in diet-induced hypercholesterolemic rats. Life Sciences. 79:324-330.
  • Li SL, Lin G, Chan SW, Li P. (2001) Determination of the major isosteroidal alkaloids in bulbs of Fritillaria by high performance liquid chromatography coupled with evaporative light scattering detector. Journal of Chromatography A. 909:207-214.
  • Sum TSW, Chan SW, Rudd JA, Yeung JHK. (2001) Actions of glucocorticoids to antagonise cisplatin-induced acute and delayed emesis in ferret. European Journal of Pharmacology. 417:231-237.
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*As corresponding author